follow the A14 "Adriatica" highway till the exit Poggio Imperiale for people coming from the North or exit Foggia for people coming from the South. Then follow the directions for Vieste.
Air connection with Foggia, Bari e Pescara airport.
By the means of transport of "Ferrovie dello Stato" it is possible to reach Foggia and from there to get any other place by train.